Clezutoclax
Clezutoclax is a agent-linker conjugate for ADC . Clezutoclax can be used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
1949843-71-3
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/clezutoclax.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC(C=CC(NC([C@H](C)NC([C@H](C(C)C)NC(CN(C1=O)[C@@H](C[C@@H]1N(C2=O)C(C=C2)=O)COCC[S](=O)(O)=O)=O)=O)=O)=C3)=C3CC[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O)C(O)=O)N(CC[C@H](O)CO)CCO[C@](C5)(C6)C[C@@](C[C@@]6(C7)C)(C[C@]57C)CN8C(C)=C(C(C=CC(N(CCC9=CC=C%10)CC9=C%10C(NC%11=NC%12=CC=CC=C%12S%11)=O)=N%13)=C%13C(O)=O)C=N8
Molecular Formula
C83H102N12O24S2
Molecular Weight
1715.89
References & Citations
[1]Boni V, et al. The Resurgence of Antibody Drug Conjugates in Cancer Therapeutics: Novel Targets and Payloads. Am Soc Clin Oncol Educ Book. 2020 Mar;40:1-17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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