Cholest-5-ene-3ß,22 (S) -diol
Cholest-5-ene-3ß,22 (S) -diol ((22S) -Hydroxycholesterol) is an orally active oxysterol with no significant cytotoxic, oxidative, or inflammatory effects on human prokaryotic leukemia cells. Cholest-5-ene-3ß,22 (S) -diol inhibits weight gain and increased serum triacylglycerol (TAG) levels in rat models[1][2].
Product Specifications
CAS Number
22348-64-7
Product Name Alternative
(22S) -Hydroxycholesterol
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
ATP-binding cassette (ABC) transporters; LXR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cholest-5-ene-3-22-s-diol.html
Purity
98.6
Solubility
10 mM in DMSO
Smiles
C[C@]12[C@](CC[C@]1([H])[C@H](C)[C@@H](O)CCC(C)C)([H])[C@@](CC=C3C[C@H]4O)([H])[C@@](CC2)([H])[C@]3(CC4)C
Molecular Formula
C27H46O2
Molecular Weight
402.65
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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