Z-Leu-Leu-Glu-βNA

Z-Leu-Leu-Glu-βNA (Z-Leu-Leu-Glu-β-naphthylamide) is a substrate for determination of the glutamylpeptidyl-peptide hydrolase activity of the 20S proteasome[1].

Product Specifications

CAS Number

[75873-85-7]

Product Name Alternative

Z-Leu-Leu-Glu-β-naphthylamide

UNSPSC

12352209

Hazard Statement

H302-H315-H319-H335

Target

Proteasome

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/z-leu-leu-glu-βna.html

Solubility

10 mM in DMSO

Smiles

O=C([C@H](CCC(O)=O)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC(OCC1=CC=CC=C1)=O)=O)=O)NC2=CC(C=CC=C3)=C3C=C2

Molecular Formula

C35H44N4O7

Molecular Weight

632.75

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Reidlinger J, et al. Catalytic properties of 26 S and 20 S proteasomes and radiolabeling of MB1, LMP7, and C7 subunits associated with trypsin-like and chymotrypsin-like activities. J Biol Chem. 1997 Oct 3;272 (40) :24899-905.