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20α,22R-Dihydroxycholesterol

Product Specifications

UNSPSC Description

20α,22R-Dihydroxycholesterol is an endogenous metabolic intermediate. 20α,22R-Dihydroxycholesterol involved in the biosynthesis of cholesterol to steroid hormones[1].

Target Antigen

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/20α-22r-dihydroxycholesterol.html

Solubility

10 mM in DMSO

Smiles

C[C@@]1([C@@]2([H])[C@@](C)(O)[C@H](O)CCC(C)C)[C@](CC2)([H])[C@@](CC=C(C3)[C@@]4(CC[C@@H]3O)C)([H])[C@]4([H])CC1

Molecular Weight

418.65

References & Citations

[1]Mast N, et, al. Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1. J Biol Chem. 2011 Feb 18;286(7):5607-13.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-137178/20α-22R-Dihydroxycholesterol-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-137178/

Clinical Information

No Development Reported

CAS Number

596-94-1

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