20α,22R-Dihydroxycholesterol

20α,22R-Dihydroxycholesterol is an endogenous metabolic intermediate. 20α,22R-Dihydroxycholesterol involved in the biosynthesis of cholesterol to steroid hormones[1].

Product Specifications

CAS Number

[596-94-1]

UNSPSC

12352211

Hazard Statement

H315-H319-H335

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/20α-22r-dihydroxycholesterol.html

Solubility

10 mM in DMSO

Smiles

C[C@@]1([C@@]2([H])[C@@](C)(O)[C@H](O)CCC(C)C)[C@](CC2)([H])[C@@](CC=C(C3)[C@@]4(CC[C@@H]3O)C)([H])[C@]4([H])CC1

Molecular Formula

C27H46O3

Molecular Weight

418.65

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Mast N, et, al. Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1. J Biol Chem. 2011 Feb 18;286 (7) :5607-13.