Oxetorone (fumarate)

Oxetorone fumarate is a non-selective, orally active serotonin antagonist. Oxetorone fumarate is an antimigraine agent[1].

Product Specifications

CAS Number

[34522-46-8]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/oxetorone-fumarate.html

Solubility

10 mM in DMSO

Smiles

O=C(O)/C=C/C(O)=O.CN(C)CC/C=C1C2=C(COC3=CC=CC=C/13)C4=CC=CC=C4O2

Molecular Formula

C25H25NO6

Molecular Weight

435.47

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Deguigne M, et al. New evidence for oxetorone toxicity. Clin Toxicol (Phila) . 2017 Feb;55 (2) :142-146.|[2]Barchewitz G, et al. Oxetorone-induced hyperprogesteronemia and the development of uterine decidual lesions in rats. Arzneimittelforschung. 1984;34 (9) :1007-10.