β-Secretase Inhibitor II
β-Secretase Inhibitor II is a β-Secretase inhibitor. β-Secretase Inhibitor II is a simple tripeptide aldehyde (IC50=700 nM for inhibition of total Aβ and IC50=2.5 μM for Aβ1–42) . β-Secretase Inhibitor II can be used for the research of Alzheimer's disease[1].
Product Specifications
CAS Number
263563-09-3
UNSPSC
12352005
Target
Beta-secretase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/β-secretase-inhibitor-ii.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@H](C=O)CC(C)C)[C@H](CC(C)C)NC([C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)=O
Molecular Formula
C25H39N3O5
Molecular Weight
461.59
References & Citations
[1]Abbenante, G., et al. Inhibitors of β-Amyloid Formation Based on the β-Secretase Cleavage Site. Biochemical and Biophysical Research Communications. 2000; 268 (1), 133–135.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC471893-100 1x 100 µL
CD10 (Membrane Metalloendopeptidase) (MME/1893), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC041950-500 1x 500 µL
Bcl-6 (Follicular Lymphoma Marker) (rBCL6/1527), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC681865-500 1x 500 µL
Napsin A (Lung Adenocarcinoma Marker) (NAPSA/1865R), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details