Ac-DNLD-CHO
Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is a Caspase-3/7 inhibitor (IC50: 9.89, 245 nM respectively; Kiapp: 0.68, 55.7 nM respectively) . Ac-DNLD-CHO can be used for research of caspase-mediated apoptosis diseases, such as neurodegenerative disorders and viral infection diseases[1].
Product Specifications
CAS Number
775289-20-8
Product Name Alternative
Ac-Asp-Asn-Leu-Asp-CHO
UNSPSC
12352209
Target
Caspase
Type
Peptides
Related Pathways
Apoptosis
Applications
COVID-19-anti-virus
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ac-dnld-cho.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CC(C)C)C(N[C@H](C=O)CC(O)=O)=O)[C@H](CC(N)=O)NC([C@@H](NC(C)=O)CC(O)=O)=O
Molecular Formula
C20H31N5O10
Molecular Weight
501.49
References & Citations
[1]Yoshimori A, et al. Structural and functional definition of the specificity of a novel caspase-3 inhibitor, Ac-DNLD-CHO. BMC Pharmacol. 2007 Jun 27;7:8.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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