IDH-C227

IDH-C227 is a potent and selective IDH1R132H inhibitor. IDH-C227 has anticancer effcts[1].

Product Specifications

CAS Number

[1355324-14-9]

UNSPSC

12352005

Target

Isocitrate Dehydrogenase (IDH)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/idh-c227.html

Solubility

10 mM in DMSO

Smiles

N#CC1=CC=C(NCC(N(C(C2=C(C)C=CC=C2)C(NC3CCCCC3)=O)C4=CC(F)=CC=C4)=O)C=C1

Molecular Formula

C30H31FN4O2

Molecular Weight

498.59

References & Citations

[1]Hanumantha Rao Madala, et al. Beyond Brooding on Oncometabolic Havoc in IDH-Mutant Gliomas and AML: Current and Future Therapeutic Strategies. Cancers (Basel) . 2018 Feb 11;10 (2) :49.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

IDH1

Curated Selection

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