IDH-C227
IDH-C227 is a potent and selective IDH1R132H inhibitor. IDH-C227 has anticancer effcts[1].
Product Specifications
CAS Number
[1355324-14-9]
UNSPSC
12352005
Target
Isocitrate Dehydrogenase (IDH)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/idh-c227.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC=C(NCC(N(C(C2=C(C)C=CC=C2)C(NC3CCCCC3)=O)C4=CC(F)=CC=C4)=O)C=C1
Molecular Formula
C30H31FN4O2
Molecular Weight
498.59
References & Citations
[1]Hanumantha Rao Madala, et al. Beyond Brooding on Oncometabolic Havoc in IDH-Mutant Gliomas and AML: Current and Future Therapeutic Strategies. Cancers (Basel) . 2018 Feb 11;10 (2) :49.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IDH1
Curated Selection
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