Levamisole-d5 (hydrochloride)

Levamisole-d5 (hydrochloride) is the deuterium labeled Levamisole hydrochloride. Levamisole ((-) -Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV[1][2].

Product Specifications

CAS Number

[1246819-64-6]

Product Name Alternative

(-) -Tetramisole-d5 hydrochloride

UNSPSC

12352005

Hazard Statement

H301, H311, H331, H361

Target

HSV; Isotope-Labeled Compounds; Parasite

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others

Field of Research

Infection; Neurological Disease

Purity

99.99

Solubility

10 mM in DMSO

Smiles

[2H]C1=C([2H])C([2H])=C([2H])C([2H])=C1[C@@]2([H])CN3C(SCC3)=N2.Cl

Molecular Formula

C11H8D5ClN2S

Molecular Weight

245.78

Precautions

H301, H311, H331, H361

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Centers for Disease Control and Prevention (CDC) . Agranulocytosis associated with cocaine use - four States, March 2008-November 2009.MMWR Morb Mortal Wkly Rep. 2009 Dec 18;58 (49) :1381-5.|[3]Zhu NY, et al. Agranulocytosis after consumption of cocaine adulterated with levamisole. Ann Intern Med. 2009 Feb 17;150 (4) :287-9.|[4]Van Belle H. Alkaline phosphatase. I. Kinetics and inhibition by levamisole of purified isoenzymes from humans. Clin Chem. 1976 Jul;22 (7) :972-6.|[5]Friedlaender MH, et al. The treatment of herpetic reinfection with levamisole. Am J Ophthalmol. 1978 Aug;86 (2) :245-9.