SARS-CoV MPro-IN-1
SARS-CoV MPro-IN-1 is a SARS-CoV-2 3CLpro covalent inhibitor, with an IC50 of 40 nM. SARS-CoV MPro-IN-1 shows good anti-SARS-CoV-2-infection activity in cell culture with an EC50 of 0.33 μM. SARS-CoV MPro-IN-1 has the potential for COVID-19 research[1].
Product Specifications
CAS Number
2413716-71-7
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sars-cov-mpro-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC2=CC=CC=C2N1)N[C@H](C(N[C@H](C=O)C[C@H](CCN3)C3=O)=O)CC4=CC(F)=CC=C4
Molecular Formula
C25H25FN4O4
Molecular Weight
464.49
References & Citations
[1]Dai W, et al. Structure-Based Design, Synthesis and Biological Evaluation of Peptidomimetic Aldehydes as a Novel Series of Antiviral Drug Candidates Targeting the SARS-CoV-2 Main Protease. bioRxiv; 2020.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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