Resolvin D3
Resolvin D3 (RvD3) is a docosahexaenoic acid (DHA) derived mediator. Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation[1][2].
Product Specifications
CAS Number
916888-47-6
Product Name Alternative
RvD3
UNSPSC
12352211
Hazard Statement
H225-H319
Target
AMPK; Autophagy
Type
Reference compound
Related Pathways
Autophagy; Epigenetics; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/resolvin-d3.html
Concentration
265.6 μM * 250 μL in Ethanol
Purity
95.0
Solubility
10 mM in DMSO
Smiles
CC/C=C\C[C@H](O)/C=C/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCC(O)=O
Molecular Formula
C22H32O5
Molecular Weight
376.49
Precautions
P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501
References & Citations
[1]Hildur H Arnardottir, et al. Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation. J Immunol. 2016 Sep 15;197 (6) :2362-8.|[2]Jennifer K Colby, et al. Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia. Am J Pathol. 2016 Jul;186 (7) :1801-1813.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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