(+/-) -Epigallocatechin Gallate-13C3
(+/-) -Epigallocatechin Gallate-13C3 is the 13C-labeled (-) -Epigallocatechin Gallate. (-) -Epigallocatechin Gallate is a tea flavonoid with potent antioxidant, antiinflammatory, and anticarcinogenic properties. (-) -Epigallocatechin Gallate is reported to inhibit EGFR signaling and thereby exert anticancer effects[1]. (-) -Epigallocatechin Gallate (EGCG) is a glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) inhibitor. Epigallocatechin-3-gallate induces oxidative phosphorylation (OXPHOS) by activating cytochrome c oxidase.
Product Specifications
UNSPSC
12352005
Target
Autophagy; Endogenous Metabolite; Ferroptosis; HIV; Mitochondrial Metabolism; Oxidative Phosphorylation; Reactive Oxygen Species (ROS)
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/epigallocatechin-gallate-13c3.html
Solubility
10 mM in DMSO
Smiles
O=C(O[13C@H]1[13C@@H](C2=CC(O)=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C3[13CH2]1)C4=CC(O)=C(O)C(O)=C4
Molecular Formula
C19 13C3H18O11
Molecular Weight
461.35
References & Citations
Isocitrate dehydrogenase
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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