Streptazolin

Streptazolin is an antibiotic. Streptazolin increases bacterial killing and elaboration of immunostimulatory cytokines by macrophages in vitro. Streptazolin stimulates the macrophage NF-κB pathway via PI3K signaling[1][2].

Product Specifications

CAS Number

[80152-07-4]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Antibiotic

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/streptazolin.html

Purity

98.65

Solubility

10 mM in DMSO

Smiles

C/C=C1C([C@@]2([H])[C@@](O3)([H])[C@H]/1O)=CCCN2C3=O

Molecular Formula

C11H13NO3

Molecular Weight

207.23

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Groenhagen U, et al. Streptopyridines, volatile pyridine alkaloids produced by Streptomyces sp. FORM5. Beilstein J Org Chem. 2014;10:1421-1432. Published 2014 Jun 24. |[2]Perry JA, et al. A macrophage-stimulating compound from a screen of microbial natural products. J Antibiot (Tokyo) . 2015;68 (1) :40-46.