T-705RMP
T-705RMP, a phosphorylated metabolite of T-705, exhibits a very weak inhibitory effect on the IMP dehydrogenase (IMPDH) activities of the host cells, with an IC50 of 601 μM[1].
Product Specifications
CAS Number
356783-08-9
UNSPSC
12352005
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/t-705rmp.html
Solubility
10 mM in DMSO
Smiles
O=C1N([C@@H]([C@H](O)[C@@H]2O)O[C@@H]2COP(O)(O)=O)C=C(F)N=C1C(N)=O
Molecular Formula
C10H13FN3O9P
Molecular Weight
369.20
References & Citations
[1]Furuta Y, et al. Mechanism of action of T-705 against influenza virus. Antimicrob Agents Chemother. 2005;49 (3) :981‐986.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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