Chrysamine G
Product Specifications
UNSPSC Description
Chrysamine G, a carboxylic acid analogue of Congo Red, can be used as a probe of amyloid deposition in Alzheimer's disease. Chrysamine G also can inhibit Aβ-induced toxicity in PC12 cells[1][2].
Target Antigen
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/chrysamine-g.html
Solubility
10 mM in DMSO
Smiles
O=C(O[Na])C1=C(O)C=CC(/N=N/C2=CC=C(C3=CC=C(/N=N/C4=CC(C(O[Na])=O)=C(O)C=C4)C=C3)C=C2)=C1
Molecular Weight
526.41
References & Citations
[1]Klunk WE, et, al. Chrysamine-G binding to Alzheimer and control brain: autopsy study of a new amyloid probe. Neurobiol Aging. Jul-Aug 1995;16(4):541-8.|[2]Klunk WE, et, al. Chrysamine-G, a lipophilic analogue of Congo red, inhibits A beta-induced toxicity in PC12 cells. Life Sci. 1998;63(20):1807-14.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-136480/Chrysamine-G-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-136480/
Clinical Information
No Development Reported
CAS Number
6472-91-9
Curated Selection
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