Polyoxin D

Polyoxin D (Polyoxorim), a polyoxin antibiotic fungicide, is a potent chitin synthetase inhibitor[1][2].

Product Specifications

CAS Number

[22976-86-9]

Product Name Alternative

Polyoxorim

UNSPSC

12352005

Target

Antibiotic; Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/polyoxin-d.html

Solubility

10 mM in DMSO

Smiles

OC(C(C(N1)=O)=CN([C@H]2[C@H](O)[C@H](O)[C@@H]([C@H](NC([C@H]([C@@H]([C@H](COC(N)=O)O)O)N)=O)C(O)=O)O2)C1=O)=O

Molecular Formula

C17H23N5O14

Molecular Weight

521.39

References & Citations

[1]B Bowers, et al. Effect of polyoxin D on chitin synthesis and septum formation in Saccharomyces cerevisiae. J Bacteriol. 1974 Aug;119 (2) :564-75.|[2]J M Becker, et al. Polyoxin D inhibits growth of zoopathogenic fungi. Antimicrob Agents Chemother. 1983 Jun;23 (6) :926-9.