Polyoxin D
Polyoxin D (Polyoxorim), a polyoxin antibiotic fungicide, is a potent chitin synthetase inhibitor[1][2].
Product Specifications
CAS Number
22976-86-9
Product Name Alternative
Polyoxorim
UNSPSC
12352005
Target
Antibiotic; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/polyoxin-d.html
Solubility
10 mM in DMSO
Smiles
OC(C(C(N1)=O)=CN([C@H]2[C@H](O)[C@H](O)[C@@H]([C@H](NC([C@H]([C@@H]([C@H](COC(N)=O)O)O)N)=O)C(O)=O)O2)C1=O)=O
Molecular Formula
C17H23N5O14
Molecular Weight
521.39
References & Citations
[1]B Bowers, et al. Effect of polyoxin D on chitin synthesis and septum formation in Saccharomyces cerevisiae. J Bacteriol. 1974 Aug;119 (2) :564-75.|[2]J M Becker, et al. Polyoxin D inhibits growth of zoopathogenic fungi. Antimicrob Agents Chemother. 1983 Jun;23 (6) :926-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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