M-Chloramphenicol

M-Chloramphenicol (m-threo-Chloramphenicol) is an impurity of Chloramphenicol. Chloramphenicol, a broad-spectrum antibiotic, acts as a potent inhibitor of bacterial protein biosynthesis[1].

Product Specifications

CAS Number

[7411-65-6]

Product Name Alternative

M-threo-Chloramphenicol

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Antibiotic

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/m-chloramphenicol.html

Solubility

10 mM in DMSO

Smiles

O=N(C1=CC=CC([C@H]([C@H](NC(C(Cl)Cl)=O)CO)O)=C1)=O

Molecular Formula

C11H12Cl2N2O5

Molecular Weight

323.13

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Polikanov YS, et al. The Mechanisms of Action of Ribosome-Targeting Peptide Antibiotics. Front Mol Biosci. 2018;5:48. Published 2018 May 14.|[2]Berendsen BJ, et al. Discrimination of eight chloramphenicol isomers by liquid chromatography tandem mass spectrometry in order to investigate the natural occurrence of chloramphenicol. Anal Chim Acta. 2011;700 (1-2) :78-85.