N, N'-Dinitrosopiperazine-d8
N, N'-Dinitrosopiperazine-d8 is the deuterium labeled N, N'-Dinitrosopiperazine[1]. N, N'-Dinitrosopiperazine (1,4-Dinitrosopiperazine; DNP) is a carcinogen with specificity for nasopharyngeal epithelium and facilitates NPC metastasis. N, N'-Dinitrosopiperazine regulates multiple signaling pathways through protein phosphorylation, including LYRIC at serine 568[2].
Product Specifications
CAS Number
69340-07-4
Product Name Alternative
1,4-Dinitrosopiperazine-d8; DNP-d8
UNSPSC
12352005
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
O=NN1C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C1([2H])[2H])N=O
Molecular Formula
C4D8N4O2
Molecular Weight
152.18
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Damao Huang, et al. Identification of Novel Signaling Components in N, N'-dinitrosopiperazine-mediated Metastasis of Nasopharyngeal Carcinoma by Quantitative Phosphoproteomics. BMC Cancer. 2014 Apr 5;14:243.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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