Rabacfosadine (succinate)
Product Specifications
UNSPSC Description
Rabacfosadine (GS-9219) succinate, a novel proagent of the nucleotide analogue PMEG, is designed as a cytotoxic agent that preferentially targets lymphoid cells[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rabacfosadine-succinate.html
Solubility
10 mM in DMSO
Smiles
OC(CCC(O)=O)=O.CCOC([C@H](C)NP(COCCN1C2=NC(N)=NC(NC3CC3)=C2N=C1)(N[C@@H](C)C(OCC)=O)=O)=O
Molecular Weight
644.61
References & Citations
[1]Reiser H, et al. GS-9219--a novel acyclic nucleotide analogue with
potent antineoplastic activity in dogs with spontaneous non-Hodgkin's lymphoma.
Clin Cancer Res. 2008 May 1;14(9):2824-32.|[2]De Clercq E. Tanovea® for the treatment of lymphoma in dogs. Biochem Pharmacol. 2018 Aug;154:265-269.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-13640A/Rabacfosadine-succinate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-13640A/
Clinical Information
Phase 2
CAS Number
1431856-99-3
Curated Selection
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