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ML338

ML338 is a selective small molecule inhibitor probe of non-replicating Mycobacterium tuberculosis bacilli and is against the non-replicating M. tuberculosis with IC90 and IC99 values of 1 μM and 4 μM, respectively by CFU. ML338 is a invaluable tool for identifying both essential functions and vulnerabilities of the M. tuberculosis bacilli in the nutrient deprivation states. ML338 can be used for the study of M. tuberculosis chemotherapy[1].

Product Specifications

CAS Number

1630160-25-6

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ml338.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC=C(C2=NN=C(SCC3=CN(C4=CC=CC=C4)N=N3)O2)C=C1

Molecular Formula

C17H12ClN5OS

Molecular Weight

369.83

References & Citations

[1]Partha P. Nag, et al. Elucidation of the Physiology of Non-Replicating, Drug Tolerant Mycobacterium tuberculosis With the Aid of the Small Molecule Probe ML338. Review

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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