(Rac) -3′-Hydroxy simvastatin
(Rac) -3′-Hydroxy simvastatin is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM[1][2].
Product Specifications
CAS Number
[126313-98-2]
UNSPSC
12352005
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/rac-3-hydroxy-simvastatin.html
Purity
99.71
Solubility
10 mM in DMSO
Smiles
CC(O)C(C)(C)C(OC1CC(C)C=C2C=CC(C)C(CCC3CC(O)CC(O3)=O)C12)=O
Molecular Formula
C25H38O6
Molecular Weight
434.57
References & Citations
[1]Slater, E.E., et al. Mechanism of action and biological profile of HMG CoA reductase inhibitors. A new therapeutic alternative. Drugs, 1988. 36 Suppl 3: p. 72-82.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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