9-cis-β-Carotene

9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal. 9-cis-β-Carotene inhibits photoreceptor degeneration and restores retinal function in vivo. 9-cis-β-Carotene has the potential for the study of congenital stationary night blindness and fundus albipunctatus[1].

Product Specifications

CAS Number

[13312-52-2]

Product Name Alternative

9Z β-Carotene

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/9-cis-β-carotene.html

Purity

Solubility

10 mM in DMSO

Smiles

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(/C=C/C=C(\C=C\C2=C(C)CCCC2(C)C)C)C)C(C)(C)CCC1

Molecular Formula

C40H56

Molecular Weight

536.87

References & Citations

[1]Sher I, et al.Synthetic 9-cis-beta-carotene inhibits photoreceptor degeneration in cultures of eye cups from rpe65rd12 mouse model of retinoid cycle defect.Sci Rep. 2018 Apr 17;8 (1) :6130.