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AHR antagonist 5 (hemimaleate)

AHR antagonist 5 hemimaleate, a potent and orally active aryl hydrocarbon receptor (AHR) antagonist, has an IC50 of [1].

Product Specifications

UNSPSC

12352005

Target

Aryl Hydrocarbon Receptor

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ahr-antagonist-5-hemimaleate.html

Solubility

10 mM in DMSO

Smiles

CC(C1=C2N(N=C1)C(N[C@H]3CC(C4=CC=CC=C4N5)=C5CC3)=NC(C6=CN=CC(F)=C6)=N2)C.O=C(O)/C=C\C(O)=O.[1/2]

Molecular Formula

C27H26O2FN7

Molecular Weight

499.55

References & Citations

[1]Alfredo C. Castro, et al. Indole ahr inhibitors and uses thereof. WO2018195397A2.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 1

Frequently Asked Questions

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