R-BC154 (acetate)
R-BC154 acetate is a selective fluorescent α9β1 integrin antagonist. R-BC154 acetate acts as a useful high affinity, activation dependent integrin probe, which can be used to investigate α9β1 and α4β1 integrin binding activity[1].
Product Specifications
UNSPSC
12352005
Target
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/r-bc154-acetate.html
Solubility
10 mM in DMSO
Smiles
CC(O)=O.CC/[N+](CC)=C1C=C2OC3=C(C=CC(N(CC)CC)=C3)C(C4=CC=C(S(NCC5=CN([C@H]6CN(S(=O)(C7=CC=CC=C7)=O)[C@H](C(N[C@H](C(O)=O)CC8=CC=C(OC(N9CCCC9)=O)C=C8)=O)C6)N=N5)(=O)=O)C=C4S(=O)([O-])=O)=C2C=C\1
Molecular Formula
C57H65N9O15S3
Molecular Weight
1212.37
References & Citations
[1]Design, synthesis and binding properties of a fluorescent α9β1/α4β1 integrin antagonist and its application as an in vivo probe for bone marrow haemopoietic stem cells. Org Biomol Chem. 2014 Feb 14;12 (6) :965-78.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Isoform
α9β1
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