(S, R, S) -AHPC-C5-NH2 (dihydrochloride)
(S, R, S) -AHPC-C5-NH2 (VH032-C5-NH2) dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader[1].
Product Specifications
CAS Number
2415256-20-9
Product Name Alternative
VH032-C5-NH2 (dihydrochloride)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-r-s-ahpc-c5-nh2-dihydrochloride.html
Purity
97.8
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1N(C([C@@H](NC(CCCCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2.Cl.Cl
Molecular Formula
C28H43Cl2N5O4S
Molecular Weight
616.64
Precautions
H302, H315, H319, H335
References & Citations
[1]Lijie Peng, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10 (5) :767-772.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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