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(S, R, S) -AHPC-C5-NH2 (dihydrochloride)

(S, R, S) -AHPC-C5-NH2 (VH032-C5-NH2) dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader[1].

Product Specifications

CAS Number

[2415256-20-9]

Product Name Alternative

VH032-C5-NH2 (dihydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/s-r-s-ahpc-c5-nh2-dihydrochloride.html

Purity

97.8

Solubility

10 mM in DMSO

Smiles

O=C([C@H]1N(C([C@@H](NC(CCCCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2.Cl.Cl

Molecular Formula

C28H43Cl2N5O4S

Molecular Weight

616.64

Precautions

H302, H315, H319, H335

References & Citations

[1]Lijie Peng, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10 (5) :767-772.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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