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(S, R, S) -AHPC-C7-amine (dihydrochloride)

(S, R, S) -AHPC-C7-amine dihydrochloride is the dihydrochloride form of (S, R, S) -AHPC-C7-amine (HY-136186) . (S, R, S) -AHPC-C7-amine is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker. (S, R, S) -AHPC-C7-amine can be used for estrogen-related receptor α (ERRα) PROTAC degrader[1][2].

Product Specifications

CAS Number

[2415256-17-4]

Product Name Alternative

VH032-C7-amine (dihydrochloride)

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/s-r-s-ahpc-c7-amine-dihydrochloride.html

Solubility

10 mM in DMSO

Smiles

NCCCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)=O)=O.Cl.Cl

Molecular Formula

C30H47Cl2N5O4S

Molecular Weight

644.70

References & Citations

[1]Plewe MB, et al. Compounds and methods of treating diseases. WO2022068933A1. 2022-04-07.|[2]Peng L, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10 (5) :767-772.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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