(S, R, S) -AHPC-C7-amine
(S, R, S) -AHPC-C7-amine (VH032-C7-amine) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader[1].
Product Specifications
CAS Number
[2306389-04-6]
Product Name Alternative
VH032-C7-amine
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-r-s-ahpc-c7-amine.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1N(C([C@@H](NC(CCCCCCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2
Molecular Formula
C30H45N5O4S
Molecular Weight
571.77
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Lijie Peng, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10 (5) :767-772.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)
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