Mal-amino-sulfo

Mal-amino-sulfo is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[158018-81-6]

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mal-amino-sulfo.html

Solubility

10 mM in DMSO

Smiles

O=C(ON1C(C(S(=O)(O)=O)CC1=O)=O)CCCN2C(C=CC2=O)=O

Molecular Formula

C12H12N2O9S

Molecular Weight

360.30

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers

Curated Selection

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