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MCHR1 antagonist 3

MCHR1 antagonist 3 is a potent the melanin-concentrating hormone receptor-1 (MCHR1) antagonist. MCHR1 antagonist 3 is used to regulate energy metabolism[1].

Product Specifications

CAS Number

[1069622-60-1]

UNSPSC

12352005

Target

MCHR1 (GPR24)

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/mchr1-antagonist-3.html

Solubility

10 mM in DMSO

Smiles

O=C(N1C2CC3=C(C=CC=C3)C2)N(CC)C4(CCN(CC5=CC=C(N6CCCC6)C=C5)CC4)C1=O

Molecular Formula

C29H36N4O2

Molecular Weight

472.62

References & Citations

[1]Rowbottom MW, et al. Synthesis and structure-activity relationships of spirohydantoin-derived small-moleculeantagonists of the melanin-concentrating hormone receptor-1 (MCH-R1) . Bioorg Med Chem Lett. 2007 Apr 15;17 (8) :2171-8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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