Aldehyde-benzyl-PEG5-alkyne

Aldehyde-benzyl-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Aldehyde-benzyl-PEG5-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[1378928-83-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aldehyde-benzyl-peg5-alkyne.html

Purity

97.09

Solubility

10 mM in DMSO

Smiles

O=CC1=CC=C(C=C1)OCCOCCOCCOCCOCC#C

Molecular Formula

C18H24O6

Molecular Weight

336.38

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562