APN-PEG4-PFP
Product Specifications
UNSPSC Description
APN-PEG4-PFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. APN-PEG4-PFP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/apn-peg4-pfp.html
Solubility
10 mM in DMSO
Smiles
FC1=C(OC(CCOCCOCCOCCOCCNC(C2=CC=C(C#CC#N)C=C2)=O)=O)C(F)=C(F)C(F)=C1F
Molecular Weight
584.49
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-136030/APN-PEG4-PFP-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-136030/
Clinical Information
No Development Reported
Curated Selection
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