DBCO-NHCO-PEG2-CH2COOH
Product Specifications
UNSPSC Description
DBCO-NHCO-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-NHCO-PEG2-CH2COOH is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dbco-nhco-peg2-ch2cooh.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CC2=C(C#CC3=C1C=CC=C3)C=CC=C2)CCNC(CCOCCOCCC(O)=O)=O
Molecular Weight
464.51
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-135935/DBCO-NHCO-PEG2-CH2COOH-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-135935/
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1483655-01 0.02 mg (E-Coli)
Recombinant Sulfolobus islandicus filamentous virus Putative glycosyltransferase 45 (SIFV0045)
Ask
View Details MBS1483655-02 0.02 mg (Yeast)
Recombinant Sulfolobus islandicus filamentous virus Putative glycosyltransferase 45 (SIFV0045)
Ask
View Details 
MBS1483655-03 0.1 mg (E-Coli)
Recombinant Sulfolobus islandicus filamentous virus Putative glycosyltransferase 45 (SIFV0045)
Ask
View Details MBS1483655-04 0.1 mg (Yeast)
Recombinant Sulfolobus islandicus filamentous virus Putative glycosyltransferase 45 (SIFV0045)
Ask
View Details 
MBS1483655-05 0.02 mg (Baculovirus)
Recombinant Sulfolobus islandicus filamentous virus Putative glycosyltransferase 45 (SIFV0045)
Ask
View Details MBS1483655-06 0.02 mg (Mammalian-Cell)
Recombinant Sulfolobus islandicus filamentous virus Putative glycosyltransferase 45 (SIFV0045)
Ask
View Details