Aniline-MPB-amino-C3-PBD

Aniline-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group. Aniline-MPB-amino-C3-PBD is a sequence-selective DNA minor-groove binding agent. Aniline-MPB-amino-C3-PBD acts as the payload for ADCs. Antimicrobial activity[1].

Product Specifications

CAS Number

[2412923-79-4]

UNSPSC

12352203

Target

ADC Payload; Bacterial

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aniline-mpb-amino-c3-pbd.html

Solubility

10 mM in DMSO

Smiles

O=C(N(CCCC1)[C@]1([H])CN2)C3=C2C=C(OCCCC(NC4=CN(C)C(C(NC5=CC=C(C6=CN(C)C(C(NC7=CC=C(N)C=C7)=O)=C6)C=C5)=O)=C4)=O)C(OC)=C3

Molecular Formula

C42H46N8O6

Molecular Weight

758.86

References & Citations

[1]David Edwin Thurston, et al. Polycyclic amides as cytotoxic agents. WO2020049286A1.

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Pyrrolobenzodiazepines

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS1399172-01 0.05 mg (E-Coli)

Recombinant Chromobacterium violaceum Deoxyribose-phosphate aldolase (deoC)

Ask

View Details

MBS1399172-02 0.05 mg (Yeast)

Recombinant Chromobacterium violaceum Deoxyribose-phosphate aldolase (deoC)

Ask

View Details

MBS1399172-03 0.2 mg (E-Coli)

Recombinant Chromobacterium violaceum Deoxyribose-phosphate aldolase (deoC)

Ask

View Details

MBS1399172-04 0.05 mg (Baculovirus)

Recombinant Chromobacterium violaceum Deoxyribose-phosphate aldolase (deoC)

Ask

View Details

MBS1399172-05 0.5 mg (E-Coli)

Recombinant Chromobacterium violaceum Deoxyribose-phosphate aldolase (deoC)

Ask

View Details

MBS1399172-06 0.2 mg (Yeast)

Recombinant Chromobacterium violaceum Deoxyribose-phosphate aldolase (deoC)

Ask

View Details