Aniline-MPB-amino-C3-PBD
Aniline-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group. Aniline-MPB-amino-C3-PBD is a sequence-selective DNA minor-groove binding agent. Aniline-MPB-amino-C3-PBD acts as the payload for ADCs. Antimicrobial activity[1].
Product Specifications
CAS Number
[2412923-79-4]
UNSPSC
12352203
Target
ADC Payload; Bacterial
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aniline-mpb-amino-c3-pbd.html
Solubility
10 mM in DMSO
Smiles
O=C(N(CCCC1)[C@]1([H])CN2)C3=C2C=C(OCCCC(NC4=CN(C)C(C(NC5=CC=C(C6=CN(C)C(C(NC7=CC=C(N)C=C7)=O)=C6)C=C5)=O)=C4)=O)C(OC)=C3
Molecular Formula
C42H46N8O6
Molecular Weight
758.86
References & Citations
[1]David Edwin Thurston, et al. Polycyclic amides as cytotoxic agents. WO2020049286A1.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Pyrrolobenzodiazepines
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