Detomidine carboxylic acid

Detomidine carboxylic acid is the major urinary metabolite of Detomidine. Detomidine is a synthetic α2-adrenergic agonist. Detomidine also has cardiac and respiratory effects and an antidiuretic action[1][2].

Product Specifications

CAS Number

[115664-39-6]

UNSPSC

12352005

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Endocrinology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/detomidine-carboxylic-acid.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C1=CC=CC(CC2=CN=CN2)=C1C

Molecular Formula

C12H12N2O2

Molecular Weight

216.24

References & Citations

[1]Salonen JS, et al. Identification of detomidine carboxylic acid as the major urinary metabolite of detomidine in the horse. Eur J Drug Metab Pharmacokinet. 1992 Jan-Mar;17 (1) :13-20.|[2]Virtanen R, et al. Pharmacological evidence for the involvement of alpha-2 adrenoceptors in the sedative effect of detomidine, a novel sedative-analgesic. J Vet Pharmacol Ther. 1985 Mar;8 (1) :30-7.