Detomidine carboxylic acid
Detomidine carboxylic acid is the major urinary metabolite of Detomidine. Detomidine is a synthetic α2-adrenergic agonist. Detomidine also has cardiac and respiratory effects and an antidiuretic action[1][2].
Product Specifications
CAS Number
[115664-39-6]
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Endocrinology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/detomidine-carboxylic-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=CC=CC(CC2=CN=CN2)=C1C
Molecular Formula
C12H12N2O2
Molecular Weight
216.24
References & Citations
[1]Salonen JS, et al. Identification of detomidine carboxylic acid as the major urinary metabolite of detomidine in the horse. Eur J Drug Metab Pharmacokinet. 1992 Jan-Mar;17 (1) :13-20.|[2]Virtanen R, et al. Pharmacological evidence for the involvement of alpha-2 adrenoceptors in the sedative effect of detomidine, a novel sedative-analgesic. J Vet Pharmacol Ther. 1985 Mar;8 (1) :30-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α adrenergic receptor
Available Sizes
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