KRAS inhibitor-7

KRAS inhibitor-7 is a potent KRAS G12C inhibitor, extracted from patent WO2017087528A1, compound B[1].

Product Specifications

CAS Number

[2022986-68-9]

UNSPSC

12352005

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/kras-inhibitor-7.html

Solubility

10 mM in DMSO

Smiles

C=CC(N1CCN(C2=C3C=C(Cl)[C@@]([C@@]4=C(F)C=CC=C4O)=C(F)C3=NC(N5CC(N(C)C)C5)=N2)CC1)=O

Molecular Formula

C26H27ClF2N6O2

Molecular Weight

528.98

References & Citations

[1]Liansheng Li, et al. 2-substituted quinazoline compounds comprising a substituted heterocyclic group and methods of use thereof. WO2017087528A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

K-Ras

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