CK2/PIM1-IN-1
CK2/PIM1-IN-1 is an inhibitor of CK2 and PIM1, with IC50s of 3.787 μM and 4.327 μM for CK2 and PIM1, respectively. CK2/PIM1-IN-1 is developed for the research of proliferative disorders such as cancer, as well as other kinase-associated conditions including inflammation, pain, vascular disorders, pathogenic infections and certain immunological disorders[1].
Product Specifications
CAS Number
[292640-28-9]
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Casein Kinase; Pim
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; JAK/STAT Signaling; Stem Cell/Wnt
Applications
COVID-19-anti-virus
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ck2-pim1-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=CC=CC=C1C2=CC=C(/C=C(SC(N3)=S)\C3=O)O2
Molecular Formula
C15H9NO4S2
Molecular Weight
331.37
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
References & Citations
[1]Mustapha Haddach, et al. Rhodanines and related heterocycles as kinase inhibitors. WO2010148351A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CK2; PIM1
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