Cletoquine
Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV) . Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment[1][2].
Product Specifications
CAS Number
4298-15-1
Product Name Alternative
Desethylhydroxychloroquine
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
CHIKV; Influenza Virus; Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cletoquine.html
Solubility
10 mM in DMSO
Smiles
CC(NC1=CC=NC2=CC(Cl)=CC=C12)CCCNCCO
Molecular Formula
C16H22ClN3O
Molecular Weight
307.82
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium
Frequently Asked Questions
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