Blonanserin (dihydrochloride)
Blonanserin dihydrochloride is a potent and orally active 5-HT2A and dopamine D2 receptor antagonist, with Ki values of 0.812 and 0.142 nM, respectively. Blonanserin dihydrochloride is usually acts as an atypical antipsychotic agent, and can be used for the research of extrapyramidal symptoms, excessive sedation, or hypotension[1][2].
Product Specifications
CAS Number
132812-45-4
Product Name Alternative
AD-5423 (dihydrochloride)
UNSPSC
12352005
Target
5-HT Receptor; Adrenergic Receptor; Dopamine Receptor; Sigma Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/blonanserin-dihydrochloride.html
Solubility
10 mM in DMSO
Smiles
FC1=CC=C(C2=C(CCCCCC3)C3=NC(N4CCN(CC)CC4)=C2)C=C1.Cl.Cl
Molecular Formula
C23H32Cl2FN3
Molecular Weight
440.42
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
5-HT2 Receptor; D1 Receptor; D2 Receptor; D3 Receptor; D4 Receptor; MUC2; α adrenergic receptor; α-1 microglobulin
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