Cinacalcet metabolite M4

Cinacalcet metabolite M4 is a metabolite of Cinacalcet. Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease[1][2].

Product Specifications

CAS Number

[104774-87-0]

UNSPSC

12352005

Hazard Statement

H302-H315-H318-H335

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/cinacalcet-metabolite-m4.html

Purity

86.07

Solubility

10 mM in DMSO

Smiles

NCCCC1=CC=CC(C(F)(F)F)=C1

Molecular Formula

C10H12F3N

Molecular Weight

203.20

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

References & Citations

[1]Kumar GN, et al. Metabolism and disposition of calcimimetic agent cinacalcet HCl in humans and animalmodels. Drug Metab Dispos. 2004 Dec;32 (12) :1491-500.|[2]Bushinsky DA, et al. Effect of cinacalcet on urine calcium excretion and supersaturation in genetic hypercalciuric stone-forming rats. Kidney Int. 2006 May;69 (9) :1586-92.