PROTAC BRD4 Degrader-3
PROTAC BRD4 Degrader-3 (compound 1004.1) is an efficacious PROTAC connected by ligands for von Hippel-Lindau and BRD4[1].
Product Specifications
CAS Number
[2313234-00-1]
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Epigenetic Reader Domain; PROTACs
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-brd4-degrader-3.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(C(CN(C(N=CC(F)=C3)=C3F)C4=C5)=CN2)C(C4=CC(C[S](C)(=O)=O)=C5C(NCCCCCCCCCCC(N[C@@H](C(C)(C)C)C(N(C[C@@H]6O)[C@@H](C6)C(NOC7=CC=C(C(SC=N8)=C8C)C=C7)=O)=O)=O)=O)=CN1C
Molecular Formula
C55H65F2N9O9S2
Molecular Weight
1098.29
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Peter Dragovich, et al. (4-hydroxypyrrolidin-2-yl) -hydroxamate compounds and methods of use thereof. WO2019084030A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BRD4
Curated Selection
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