Bamifylline

Bamifylline is a drug in the chemical class of xanthine that acts as a selective adenosine A1 receptor antagonist[1][2].

Product Specifications

CAS Number

2016-63-9

UNSPSC

12352005

Hazard Statement

H302

Target

Adenosine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/bamifylline.html

Solubility

10 mM in DMSO

Smiles

O=C(N1C)N(C)C2=C(N(CCN(CC)CCO)C(CC3=CC=CC=C3)=N2)C1=O

Molecular Formula

C20H27N5O3

Molecular Weight

385.46

Precautions

P264-P270-P330-P501

References & Citations

[1]Abbracchio MP, et al. Selective activity of bamifylline on adenosine A1-receptors in rat brain. Pharmacol Res Commun. 1987 Aug;19 (8) :537-45.|[2]Tomai F, et al. Effects of A1 adenosine receptor blockade by bamiphylline on ischaemic preconditioning during coronary angioplasty. Eur Heart J. 1996 Jun;17 (6) :846-53.