Depudecin
Depudecin ((-) -Depudecin) is a histone deacetylase (HDAC) inhibitor. Depudecin can be isolated from the fungus Alternaria brassicicola[1][2].
Product Specifications
CAS Number
139508-73-9
Product Name Alternative
(-) -Depudecin
UNSPSC
12352005
Target
HDAC
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/depudecin.html
Solubility
10 mM in DMSO
Smiles
C[C@@H](O)[C@@]1([H])[C@@H](O1)/C=C/[C@H]2[C@@]([C@H](O)C=C)([H])O2
Molecular Formula
C11H16O4
Molecular Weight
212.24
References & Citations
[1]Hannah T Reynolds, et al. Differential Retention of Gene Functions in a Secondary Metabolite Cluster. Mol Biol Evol. 2017 Aug 1;34 (8) :2002-2015.|[2]M Matsumoto, et al. Depudecin: a novel compound inducing the flat phenotype of NIH3T3 cells doubly transformed by ras- and src-oncogene, produced by Alternaria brassicicola. J Antibiot (Tokyo) . 1992 Jun;45 (6) :879-85.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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