3-Oxo Atorvastatin

3-Oxo Atorvastatin is an impurity of 3-Oxo Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids[1].

Product Specifications

CAS Number

[887196-30-7]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/3-oxo-atorvastatin.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C(C(C)C)N(CC[C@@H](O)CC(CC(O)=O)=O)C(C2=CC=C(F)C=C2)=C1C3=CC=CC=C3)NC4=CC=CC=C4

Molecular Formula

C33H33FN2O5

Molecular Weight

556.62

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Ramesha, B., et al. DEVELOPMENT AND VALIDATION OF A STABILITY-INDICATING GRADIENT RP-UHPLC METHOD FOR THE DETERMINATION OF IMPURITIES IN ATORVASTATIN DRUG SUBSTANCE. Journal of Liquid Chromatography & Related Technologies.2013; 37 (3), 275–297.