Descarbamoyl cefuroxime

Descarbamoyl cefuroxime is a degradation product of Cefuroxime. Descarbamoyl cefuroxime is also an intermediate for the synthesis of Cephalosporin antibiotics[1][2].

Product Specifications

CAS Number

[56271-94-4]

UNSPSC

12352005

Hazard Statement

H317-H334

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/descarbamoyl-cefuroxime.html

Solubility

10 mM in DMSO

Smiles

O=C(C(N12)=C(CO)CS[C@]2([H])[C@H](NC(/C(C3=CC=CO3)=N\OC)=O)C1=O)O

Molecular Formula

C15H15N3O7S

Molecular Weight

381.36

Precautions

P261-P272-P280-P284-P302+P352-P304+P340-P362+P364-P501

References & Citations

[1]Vercheval C, et al. Stability of 90 mg/mL cefuroxime sodium solution for administration by continuous infusion. J Chemother. 2018 Oct - Dec;30 (6-8) :371-374.|[2]Takaya T, et al. Studies on beta-lactam antibiotics. III. Synthesis and enzymatic stability of 3-acyloxymethyl-7 beta-[ (Z) -2- (2-amino-4-thiazolyl) -2- (methoxyimino) acetamido]-3-cephem-4-carboxylic acids. J Antibiot (Tokyo) . 1981 Oct;34 (10) :1300-10.