(Rac) -5-Keto Fluvastatin

(Rac) -5-Keto Fluvastatin (3-Hydroxy-5-Keto Fluvastatin) is an impurity of Fluvastatin (XU 62320) . Fluvastatin is a HMG-CoA reductase inhibitor with an IC50 of 8 nM[1].

Product Specifications

CAS Number

[1160169-39-0]

Product Name Alternative

3-Hydroxy-5-Keto Fluvastatin

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

HMG-CoA Reductase (HMGCR)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/rac-5-keto-fluvastatin.html

Solubility

10 mM in DMSO

Smiles

O=C(O)CC(O)CC(/C=C/C(N1C(C)C)=C(C2=CC=C(F)C=C2)C3=C1C=CC=C3)=O

Molecular Formula

C24H24FNO4

Molecular Weight

409.45

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Araújo FA, Rocha MA, Capettini LS, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (fluvastatin) decreases inflammatory angiogenesis in mice. APMIS. 2012 24. [Epub ahead of print]